Psychosocial Influences on Herpesvirus Latency
AbstractThere are convergent animal and human data implicating stress as a risk factor in the development and duration of primary herpesvirus infections (Rasmussen et al., 1957; Gross, 1972; Kasl et...
View ArticleMapping EBV Early Antigens in Human Cells after Microinjection of Subgenomic...
AbstractThe early antigen complex of EBV include the diffuse (EAD) and restricted (EAR) antigens which are detectable by indirect immunofluorescence (IF) using heterologous human sera and monoclonal...
View ArticleTwo Monoclonal Antibodies against Epstein-Barr Virus Proteins
AbstractThe ability of viruses to produce malignant disease in humans has been intensively studied in recent years. One of these candidate viruses is the Epstein-Barr virus (EBV). The EBV is the...
View ArticlePsychological Influences on Immunity: Making Sense of the Relationship...
AbstractDuring the last two decades there has been ample documentation of the relationship between an accumulation of negative major life events and subsequent health impairments. Although there are a...
View ArticleEnhanced SV40 Immortalization of Primary Human Epidermal Cells Following...
AbstractThe susceptibility of freshly isolated human epithelial cells to simian virus 40 (SV40) transformation is very low (1–5). It has been difficult to quantitate the sensitivity of these cells to...
View ArticleThe Transforming Activity of a Nasopharyngeal Carcinoma-Derived Epstein-Barr...
AbstractThe Epstein-Barr virus (EBV) is very efficient in growth transforming human and certain non-human B-lymphocytes into transformed lymphoblastoid cell lines (LCL’s). The LCL’s have the ability to...
View ArticleThe reliability and validity of a structured interview for the assessment of...
AbstractRespiratory infections are the leading cause of morbidity in community populations. We developed a structured interview based on the Health Review (Roseet al., Psychosom. Med. 40: 142–165,...
View ArticleChronic stress down-regulates growth hormone gene expression in peripheral...
Abstract“Pituitary” peptides are produced in both endocrine and immune cells. Acute and chronic stress can alter pituitary peptide secretion and might also influence neuroendocrine gene expression in...
View ArticleChronic stress modulates the virus-specific immune response to latent herpes...
AbstractWe compared 71 family caregivers of dementia sufferers and 58 control subjects on three different immune measures relevant to latent herpes simplex virus Type 1 (HSV-1) infection: neutralizing...
View ArticleDifferential effects of estrogen and medroxyprogesterone on basal and...
AbstractWe evaluated the influence of continual estrogen replacement therapy (ERT) as presently practiced by postmenopausal women with conjugated estrogens and medroxyprogesterone acetate (MPA) on the...
View ArticleThe Effects of Stress on the Immune System
AbstractThere are presently seven known and characterized human herpesviruses: herpes simplex virus type 1 (HSV-1), HSV-2, cytomegalovirus (CMV), varicella zoster virus (VZV), Epstein—Barr virus (EBV),...
View ArticleDepression, Immune Function, and Health in Older Adults
ConclusionIn summary, there are clearly significant immunological declines associated with depression, depressed mood, and stress. Unfortunately, these distress-related effects are magnified in elderly...
View ArticlePerceived Stress and Cellular Immunity: When Coping Counts
AbstractThis cross-sectional study investigated whether active and avoidance coping methods were differentially related to immune function depending on stress level. Perceived stress and coping method...
View ArticleGg
AbstractThe gate control theory of pain, published by Melzack and Wall in 1965, proposes that the transmission of nerve impulses from the body to the brain is modulated by a gating mechanism in the...
View ArticleSpousal Support Satisfaction as a Modifier of Physiological Responses to...
AbstractWe investigated linkages between spousal support satisfaction and affective, cortisol, and blood pressure responses to conflict in two samples, 85 newlyweds and 31 older couples, married an...
View ArticleOlder Spouses’ Cortisol Responses to Marital Conflict: Associations With...
We examined 31 older couples’ wife demand/husband withdraw communication patterns and cortisol responses to marital conflict. Regression analyses indicated that wife demand/husband withdraw sequences...
View ArticleStress-Induced Immune Dysregulation: Implications for Wound Healing,...
AbstractThe communication between the central nervous system and the immune system occurs via a complex network of bidirectional signals linking the nervous, endocrine and immune systems. The field of...
View ArticleImmune Measures in Behavioral Medicine Research: Procedures and Implications
AbstractImmune system activity is heavily influenced by the central nervous system. These interactions provide us the means to study mind–body interactions and how they affect health. In general,...
View ArticleThe Impact of Everyday Stressors on the Immune System and Health
AbstractResearch over the past three decades has clearly established that psychological stress in daily life affects clinically relevant immune outcomes including inflammatory processes, wound healing,...
View ArticleUse of ß-blockers and mortality following ovarian cancer diagnosis: a...
AbstractBackgroundExperimental data suggest that catecholamine hormones are involved in stimulating the aggressiveness of ovarian cancer, but few population-based studies have examined this...
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